Read the articles describing the technique behind our products:
Kotol D, Hober A, Strandberg L, Svensson AS, Uhlén M, Edfors F. Targeted proteomics analysis of plasma proteins using recombinant protein standards for addition only workflows.
Biotechniques. 2021;71(3):473-483. doi:10.2144/btn-2021-0047
Zeiler M, Straube WL, Lundberg E, Uhlen M, Mann M. A Protein Epitope Signature Tag (PrEST) Library Allows SILAC-based Absolute Quantification and Multiplexed Determination of Protein Copy Numbers in Cell Lines.
Molecular & Cellular Proteomics. 2012;11(3):O111.009613. doi:10.1074/mcp.O111.009613
Further reading
- Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, et al. Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism. Nat Commun. 2023;14(1):3280. doi:10.1038/s41467-023-38383-y
- Kotol D, Woessmann J, Hober A, et al. Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma. Cancers (Basel). 2023;15(19):4764. doi:10.3390/cancers15194764
- Hober A, Rekanovic M, Forsström B, et al. Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determination of total apolipoprotein(a) in human plasma. PLoS One. 2023;18(2):e0281772. doi:10.1371/journal.pone.0281772
- Woessmann J, Kotol D, Hober A, Uhlén M, Edfors F. Addressing the Protease Bias in Quantitative Proteomics. J Proteome Res. 2022;21(10):2526-2534. doi:10.1021/acs.jproteome.2c00491
- Malm M, Kuo CC, Barzadd MM, et al. Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins. Metab Eng. 2022;72:171-187. doi:10.1016/j.ymben.2022.03.009
- Karlsson MJ, Costa Svedman F, Tebani A, et al. Inflammation and Apolipoproteins Are Potential Biomarkers for Stratification of Cutaneous Melanoma Patients for Immunotherapy and Targeted Therapy. Cancer Res. 2021;81(9):2545-2555. doi:10.1158/0008-5472.CAN-20-2000
- Kotol D, Hunt H, Hober A, et al. Longitudinal Plasma Protein Profiling Using Targeted Proteomics and Recombinant Protein Standards. J Proteome Res. 2020;19(12):4815-4825. doi:10.1021/acs.jproteome.0c00194
- Hong MG, Dodig-Crnković T, Chen X, et al. Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality. Life Sci Alliance. 2020;3(10):e202000817. doi:10.26508/lsa.202000817
- Edfors F, Forsström B, Vunk H, et al. Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics. J Proteome Res. 2019;18(7):2706-2718. doi:10.1021/acs.jproteome.8b00924
- Andersson A, Remnestål J, Nellgård B, et al. Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer’s disease. Clinica Chimica Acta. 2019;494:79-93. doi:10.1016/j.cca.2019.03.243
- Hober A, Edfors F, Ryaboshapkina M, et al. Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay. Molecular & Cellular Proteomics. 2019;18(12):2433-2446. doi:10.1074/mcp.RA119.001765
- Edfors F, Boström T, Forsström B, et al. Immunoproteomics Using Polyclonal Antibodies and Stable Isotope–labeled Affinity-purified Recombinant Proteins. Molecular & Cellular Proteomics. 2014;13(6):1611-1624. doi:10.1074/mcp.M113.034140