ProteomEdge · Resources

Key Opinion Leader Voices

External perspectives from pharma, academia, clinical research and core facilities on moving proteomics from discovery toward quantitative confidence.

ProteomEdge works with scientists across pharma, academia, clinical research and core facilities to make targeted mass spectrometry-based protein quantification more robust, scalable and accessible. In this series, external voices share how multiplexed qRePS-supported workflows can help move proteomics from discovery toward quantitative confidence.

Florian Rosenberger and Ákos Végvári at HUPO 2026
Single-Cell & Spatial Proteomics

Towards quantitative confidence in single-cell proteomics

“We are particularly vulnerable to everything that happens throughout the workflow.”
— Florian Rosenberger — Assistant Professor and group leader, Karolinska Institutet, Stockholm, Sweden

How low-load testing of qRePS is informing the development of internal standards for single-cell and spatial proteomics.

Prof. Jacob Odeberg
Clinical Translation

From plasma biomarkers to recurrence risk

“A reproducible workflow gives us greater confidence that the differences we observe are biological and not caused by the measurement process.”
— Prof. Jacob Odeberg — Professor of Clinically Applied Proteomics, KTH Royal Institute of Technology / SciLifeLab, Sweden

How targeted proteomics and qRePS-supported quantification can support reproducible plasma biomarker validation across cohorts and research into more individualized thrombosis risk assessment.

Prof. Lekha Sleno
Academic Bioanalytical MS

From plasma discovery to quantitative confidence

“The more robust and comparable data we can have the better our biological insights will be.”
— Prof. Lekha Sleno — Professor, Department of Chemistry, University of Quebec in Montreal (UQAM), Canada

How combining discovery proteomics, targeted workflows and qRePS-supported quantification can improve robustness when investigating liver disease biology and biomarker candidates across cohorts.

Dr. Carina Sihlbom Wallem
Core Facility Service

Making absolute proteomics accessible

“Core facilities can play a pivotal role in bridging advanced proteomics and clinical/translational needs by acting as both technology enablers and workflow coordinators that connect all the steps of a complex process into a smooth, usable end-to-end workflow.”
— Carina Sihlbom Wallem, PhD — Head of Proteomics Core Facility (PCF), University of Gothenburg, SciLifeLab & BioMS, Sweden

A core facility perspective on lowering the barrier to robust, multiplexed absolute protein quantification for researchers across life science, translational research and precision medicine.

Dr. Tasso Miliotis
Pharma Research

Looking beyond LDL and HDL

“Moving from discovery proteomics to targeted, absolute quantification shifts biomarker work from hypothesis generation to decision-enabling measurement.”
— Tasso Miliotis, PhD — Biomarker Lead, AstraZeneca, Gothenburg, Sweden

How absolute apolipoprotein quantification can help pharma teams generate reproducible protein data across studies and explore biology that conventional lipid readouts miss.

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